The geochemical monitoring carried out on fluids released in the Central Apennines (Umbria region) evidenced seismically-induced modifications of the physic-chemical parameters in all the released fluids, including some cold waters circulating in certain carbonate rocks that are exploited for drinking purposes. The results allowed us to recognize the presence of components of diverse origin that changed the chemical composition of the water. These components, potentially dangerous for human consumption, can be considered as being "secondary effects" on local aquifers, induced by crustal deformation.